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Molfinity

WP1066 - CAS 857064-38-1

WP1066 - CAS 857064-38-1

MF-0093051-01

$42.89 USD
$42.89 USD
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Product Details

  • Bioactivity

    WP1066 is a inhibitor of JAK2 (IC50: 2.30 μM) and STAT3 (IC50: 2.43 μM) in HEL cells; shows activity to JAK2, STAT3/5, and ERK1/2, not JAK1 and JAK3. WP1066 has been used in trials studying the treatment of Melanoma, Brain Cancer, Solid Tumors, and Central Nervous System Neoplasms.

  • Target

    STAT, JAK, Apoptosis

  • Related Pathways

    Stem Cells, JAK/STAT signaling, Tyrosine Kinase/Adaptors, Angiogenesis, Apoptosis, Chromatin/Epigenetic

  • CAS Number

    857025

  • Purity

    0.9973

  • Molecular Formula

    C17H14BrN3O

  • Molecular Weight

    356.22

  • SMILES

    C[C@H](NC(=O)C(=C\c1cccc(Br)n1)\C#N)c1ccccc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound