WR99210 hydrochloride (47326-86-3 free base) - CAS 30711-93-4

WR99210 hydrochloride is a potent inhibitor of Plasmodium falciparum dihydrofolate reductase (pfDHFR), which is a major malarial drug target. It has subnanomolar potency for the wild type, double mutant and quadruple mutant dihydrofolate reductases.

Others, Parasite, DHFR

Others, Metabolism, Microbiology/Virology, DNA Damage/DNA Repair, Cell Cycle/Checkpoint

30614

0.9996

C14H19Cl4N5O2

431.14

NC1=NC(N)=NC(C)(C)N1OCCCOC2=CC(Cl)=C(Cl)C=C2Cl.[H]Cl

-20°C

Ice Packs

Small Compound