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WRN inhibitor 11 - CAS 3058317-61-3

WRN inhibitor 11 - CAS 3058317-61-3

SKU:MF-0142860-01

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  • Bioactivity

    WRN inhibitor 11 (Example 17) is an orally effective inhibitor of WRN helicase, with an IC50 of 63 nM.

  • Target

    DNA/RNA Synthesis

  • Related Pathways

    DNA Damage/DNA Repair, Cell Cycle/Checkpoint

  • CAS Number

    3058253

  • Molecular Formula

    C34H35ClF3N9O5

  • Molecular Weight

    742.15

  • SMILES

    O=C(C1=NC=NC(=C1O)C)N2CC3N(C=4C(=O)N5N=C(N=C5N(C4CC)CC(=O)NC6=CC(Cl)=C(C=C6C)C(F)(F)F)C7=CCOCC7)C(C2)CC3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound