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WRN inhibitor 2 - CAS 2923009-56-5
WRN inhibitor 2 - CAS 2923009-56-5
SKU:MF-0157057-01
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Product Details
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Bioactivity
WRN Inhibitor 2 (example 118), a potent inhibitor of the WRN (Werner Syndrome ATP-dependent helicase enzyme), exhibits a pIC50 value of 7.0 or greater [1].
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Target
DNA/RNA Synthesis
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Related Pathways
DNA Damage/DNA Repair, Cell Cycle/Checkpoint
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CAS Number
2922948
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Molecular Formula
C15H11F3N2O5S2
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Molecular Weight
420.38
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SMILES
OC1=C(C=2C=C(C(F)(F)F)SC2)NC(=O)C(C(N[C@@H]3C=CS(=O)(=O)C3)=O)=C1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound