WRN inhibitor 7 - CAS 444780-45-4

WRN inhibitor 7 (Compound h6), a potent inhibitor of Werner syndrome helicase, demonstrates effective suppression of WRN's helicase and ATPase activities with IC50 values of 9.8 μM and 15.8 μM, respectively. This compound is utilized in the study of microsatellite instable (MSI) cancers [1].

DNA/RNA Synthesis

DNA Damage/DNA Repair, Cell Cycle/Checkpoint

444780-45-4

C27H23N3O6

485.49

C(=C1C(=O)N(CC(NC2=CC=C(C)C=C2)=O)C(=O)N1)C3=C(OCC4=CC(C(O)=O)=CC=C4)C=CC=C3

-20°C

Ice Packs

Small Compound