WSF1-IN-1 - CAS 2379577-82-7

WSF1-IN-1 is an orally bioavailable small-molecule inhibitor of the WSF1 protein, designed for the investigation of WSF1-associated tumorigenesis in Wolfram syndrome. in studies using HepG2 parental and HepG2 WFS1 knockout cell lines, WSF1-IN-1 demonstrated differential inhibitory potency with IC50 values of 0.33 μM, confirming its target selectivity and mechanistic specificity in modulating WSF1-related cellular pathways.

Transmembrane Glycoprotein

Neuroscience

2379488

0.999

C20H21F3N8O

446.44

CN1C=2C(=C(C)N=C(NCC3=CN(CC=4C=CC(C(F)(F)F)=NC4)N=C3)N2)NC(=O)[C@@H]1C

-20°C

Ice Packs

Small Compound