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WX8 - CAS 232935-92-1
WX8 - CAS 232935-92-1
SKU:MF-0122212-01
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Product Details
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Bioactivity
WX8 (Ro 91-4714) is an ATP-competitive inhibitor of PIKFYVE, displaying Kd values of 0.9 nM for PIKFYVE and 340 nM for PIP4K2C. This compound inhibits lysosomal fission without affecting homotypic lysosome fusion. WX8 (Ro 91-4714) is applicable in research on autophagy-dependent cancers.
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CAS Number
232935-92-1
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Molecular Formula
C22H22N8O
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Molecular Weight
414.46
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SMILES
N(=CC1=CNC=2C=CC=CC12)NC=3N=C(N=C(N3)N4CCOCC4)NC=5C=CC=CC5
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound