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Molfinity

WYE-354 - CAS 1062169-56-5

WYE-354 - CAS 1062169-56-5

MF-0012833-01

$42.14 USD
$42.14 USD
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Product Details

  • Bioactivity

    WYE-354 (IC50=5 nM) is an effective, selective and ATP-competitive mTOR inhibitor. It blocks mTORC2/P-AKT (S473) and mTORC1/P-S6K (T389), not P-AKT (T308) . The selectivity for mTOR is higher than PI3Kα (>100-fold) and PI3Kγ (>500-fold) .

  • Target

    PI3K, Apoptosis, mTOR, Autophagy

  • Related Pathways

    Apoptosis, PI3K/Akt/mTOR signaling, Autophagy

  • CAS Number

    1062108

  • Purity

    0.9961

  • Molecular Formula

    C24H29N7O5

  • Molecular Weight

    495.53

  • SMILES

    COC(=O)Nc1ccc(cc1)-c1nc(N2CCOCC2)c2cnn(C3CCN(CC3)C(=O)OC)c2n1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound