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WYJ-2 - CAS 3029403-05-9
WYJ-2 - CAS 3029403-05-9
SKU:MF-0121540-01
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Product Details
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Bioactivity
WYJ-2, a selective agonist for toll-like receptor 2/1 (TLR2/1), demonstrates an EC50 of 18.57 nM in HEK 293T cells transiently co-transfected with human TLR2 and TLR1. It induces pyroptosis and has shown anticancer activity against non-small cell lung cancer (NSCLC) [1].
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Target
Pyroptosis, TLR
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Related Pathways
Immunology/Inflammation, Apoptosis
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CAS Number
3029403-05-9
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Molecular Formula
C17H9F2N3O4
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Molecular Weight
357.27
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SMILES
FC=1C(C2=NC(=NO2)C3=CC=4C(OC3)=CC=C(F)C4)=CC(N(=O)=O)=CC1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound