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Molfinity

WZ-3146 - CAS 1214265-56-1

WZ-3146 - CAS 1214265-56-1

MF-0093059-01

$45.88 USD
$45.88 USD
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Product Details

  • Bioactivity

    WZ3146 is a mutant-selective irreversible inhibitor of EGFR (L858R) and EGFR (E746_A750) with IC50 of 2 nM and 2 nM; does not inhibit ERBB2 phosphorylation (T798I) .

  • Target

    EGFR

  • Related Pathways

    Tyrosine Kinase/Adaptors, Angiogenesis, JAK/STAT signaling

  • CAS Number

    1214208

  • Purity

    0.9895

  • Molecular Formula

    C24H25ClN6O2

  • Molecular Weight

    464.95

  • SMILES

    CN1CCN(CC1)c1ccc(Nc2ncc(Cl)c(Oc3cccc(NC(=O)C=C)c3)n2)cc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound