XD2-149 - CAS 2710221-08-0

XD2-149 is a PROTAC compound designed to target STAT3. It is composed of the PROTAC target protein ligand Napabucasin, the E3 ligase Thalidomide, and the linker NH2-C5-Azacyclohexane-N-Boc. The conjugate of the E3 ligase and linker is Thalidomide-NH-C5-azacyclohexane-N-Boc, with Thalidomideacid serving as the active comparator for the target protein ligand.

PROTACs, STAT

Stem Cells, JAK/STAT signaling, PROTAC

2710221-08-0

C38H39N5O8

693.75

O=C(NCCN1CCC(CC1)CCCCCNC2=CC=CC=3C(=O)N(C(=O)C23)C4C(=O)NC(=O)CC4)C=5OC=6C(=O)C=7C=CC=CC7C(=O)C6C5

-20°C

Ice Packs

PROTAC