Xestospongin C - CAS 88903-69-9

Xestospongin C ((-) -Xestospongin C) is a selective inositol 1,4,5-trisphosphate receptor (IP3R) inhibitor and also inhibits sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA) . It has neuroprotective effects in APP/PS1 AD mice, improving cognitive and pathological deficits associated with Alzheimer's disease.

Calcium Channel, Apoptosis

Apoptosis, Membrane transporter/Ion channel, Metabolism

88825

C28H50N2O2

446.71

[C@@]12([N@@]3CC[C@](O1)(CCCCCC[C@]4([C@@]5(O[C@](CCCCCC[C@]2(CCC3)[H])(CC[N@]5CCC4)[H])[H])[H])[H])[H]

-20°C

Ice Packs

Natural Product