XH161-180 - CAS 3058588-52-3

XH161-180 is an effective and orally active inhibitor of ubiquitin carboxyl-terminal hydrolase 2 (USP2) . It reduces the protein levels of cyclin D and ACE2, exhibiting antiproliferative activity. XH161-180 also has potential for research in cancers and viral infections that depend on ACE2.

DUB

Ubiquitination, DNA Damage/DNA Repair, Cell Cycle/Checkpoint

3058533

C22H21BrFN3O3S2

538.45

O=C(NC1=NC(=CS1)C=2C=CC(Br)=CC2)C3=CC=C(F)C=C3NS(=O)(=O)C4CCCCC4

-20°C

Ice Packs

Small Compound