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XOR/URAT1-IN-1 - CAS 2810137-86-9

XOR/URAT1-IN-1 - CAS 2810137-86-9

MF-0147997-01

$1,383.80 USD
$1,383.80 USD
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Product Details

  • Bioactivity

    Compound II15, known as XOR/URAT1-IN-1, serves as a dual inhibitor targeting xanthine oxidoreductase (XOR) and uric acid transporter 1 (URAT1), exhibiting IC50 values of 6 nM and 12.9 μM, respectively. This compound effectively reduces uric acid levels in a mouse model of acute hyperuricemia induced by potassium oxonate and hypoxanthine.

  • Target

    OAT, Xanthine Oxidase

  • Related Pathways

    Metabolism, Membrane transporter/Ion channel

  • CAS Number

    2810137-86-9

  • Molecular Formula

    C18H13ClN2O3

  • Molecular Weight

    340.76

  • SMILES

    O=C(O)C=1C=CC(=CC1O)C2=CN=CC(=C2)NC=3C=CC=C(Cl)C3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound