XVA143 - CAS 264275-77-6

XVA143 is an integrin α/β I-like allosteric antagonist that inhibits LFA-1 (αLβ2 integrin) -dependent firm adhesion and induces an extended conformation of integrins.

Integrin

Cytoskeletal Signaling

264192

C25H21Cl2N3O8

562.36

C(NCC1=CC(O)=CC=C1)(=O)C2=CC(Cl)=C(C(N[C@@H](CNC(=O)C3=CC(O)=CC(O)=C3)C(O)=O)=O)C(Cl)=C2

-20°C

Ice Packs

Small Compound