Yadanzigan - CAS 76588-87-9

Yadanzigan (YDZG), a natural product from Brucea javanica and a specific NLRP3 inhibitor, attenuates the NF-κB pathway and reactive oxygen species generation in mitochondria, while enhancing TRIM31, which has anti-inflammatory effects and prevents lps-induced acute lung injury.

NF-κB, NOD-like Receptor (NLR), NOD, ROS

Immunology/Inflammation, NF-κB

76492

0.9998

C26H38O14

574.57

O=C1OC2CC3C(=CC(OC4OC(CO)C(O)C(O)C4O)C(O)C3(C)C5C(O)C(O)C6(OCC25C6(O)C1O)C)C

-20°C

Ice Packs

Natural Product