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YHO-13177 - CAS 912287-56-0

YHO-13177 - CAS 912287-56-0

SKU:MF-0094504-01

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  • Bioactivity

    YHO-13177 is a potent and specific inhibitor of BCRP, which enhances the cytotoxicity of SN-38 in cancer cells without affecting P-glycoprotein–mediated paclitaxel resistance in [MDR1]-transduced human leukemia [K562] cells.

  • Target

    BCRP

  • Related Pathways

    Membrane transporter/Ion channel

  • CAS Number

    912231

  • Purity

    0.9878

  • Molecular Formula

    C20H22N2O3S

  • Molecular Weight

    370.47

  • SMILES

    COc1ccc(cc1OC)C(=C\c1ccc(s1)N1CCC(O)CC1)\C#N

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound