YIGSR-Lys (N3) - CAS 2415188-59-7

YIGSR-Lys (N3) is a peptide that inhibits the tumor growth and metastasis of leukemia cells. This compound interferes with the interaction between cells and laminin I by blocking a 67 kDa laminin-binding protein, thereby reducing shear-induced eNOS expression in laminin cells. As a click chemistry reagent, YIGSR-Lys (N3) contains an azide group that undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAC) with alkynyl-containing molecules. Additionally, it can engage in strain-promoted azide-alkyne cycloaddition (SPAAC) reactions with molecules bearing DBCO or BCN groups.

NO Synthase

Immunology/Inflammation

2415188-59-7

C32H52N12O9

748.83

[C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@H](CC1=CC=C(O)C=C1)N)=O)[C@H](CC)C)=O)=O)CO)=O)(C(N[C@@H](CCCCN=[N+]=[N-])C(O)=O)=O)CCCNC(=N)N

-20°C

Ice Packs

Peptide