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YKL-05-099 - CAS 1936529-65-5
YKL-05-099 - CAS 1936529-65-5
SKU:MF-0013183-01
Regular price
$60.83 USD
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$60.83 USD
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Product Details
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Bioactivity
YKL-05-099 is a salt-inducible kinase (SIK) inhibitor. It can inhibit the activity of SIK1 (IC50: 10 nM) and SIK3 (IC50: 30 nM), and has a slightly weaker inhibitory effect on SIK2 (IC50: 40 nM) . [1]
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Target
SIK
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Related Pathways
PI3K/Akt/mTOR signaling
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CAS Number
1936459
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Purity
0.9989
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Molecular Formula
C32H34ClN7O3
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Molecular Weight
600.11
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SMILES
COc1ccc(nc1)N1C(=O)N(Cc2cnc(Nc3ccc(cc3OC)C3CCN(C)CC3)nc12)c1c(C)cccc1Cl
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound