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YL-1-9 - CAS 3064304-12-4
YL-1-9 - CAS 3064304-12-4
SKU:MF-0114736-01
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Product Details
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Bioactivity
YL-1-9 is an inhibitor that prevents the degradation of p53 by MDM2 through tight binding to the crucial hydrophobic pocket of MDM2. It can induce cell cycle arrest and apoptosis in breast cancer cells [1].
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Target
CDK, MDM-2/p53
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Related Pathways
Cell Cycle/Checkpoint, Apoptosis
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CAS Number
3064288
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Molecular Formula
C22H23F3N2O3
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Molecular Weight
420.425
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SMILES
O=C(NC1=CC=C(C(=C1)C(F)(F)F)CN2CCC(C)CC2)C3=CC=C4OCOC4=C3
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound