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Molfinity

YLIU-4-105-1 - CAS 2417685-83-5

YLIU-4-105-1 - CAS 2417685-83-5

SKU:MF-0142818-01

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  • Bioactivity

    YLIU-4-105-1 is a type II JAK2 inhibitor. Demonstrating in vivo pharmacological activity, YLIU-4-105-1 reduces splenic weight, decreases blood reticulocyte counts in a dose-dependent manner, and inhibits pSTAT5.

  • Target

    JAK

  • Related Pathways

    Tyrosine Kinase/Adaptors, Chromatin/Epigenetic, JAK/STAT signaling, Stem Cells, Angiogenesis

  • CAS Number

    2417597

  • Molecular Formula

    C32H34F3N7O2

  • Molecular Weight

    605.65

  • SMILES

    O=C(NC=1C=C(C=C(C1)C(F)(F)F)CN2CCN(CC)CC2)C=3C=CC(=C(C3)C4=NN5C=C(N=C5C=C4)NC(=O)C6CC6)C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound