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YM-202074 - CAS 299900-83-7
YM-202074 - CAS 299900-83-7
SKU:MF-0144114-01
Regular price
$2,041.92 USD
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$2,041.92 USD
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Product Details
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Bioactivity
YM-202074 is a high affinity, selective metabotropic glutamate receptor type 1 (mGlu1) antagonist. YM-202074 binds an allosteric site of the rat mGlu1 receptor with a Ki of 4.8 nM. It inhibits mGlu1-mediated inositol phosphates production (IC50 = 8.6 nM in rat cerebellar granule cells) .
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Target
Others, GluR
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Related Pathways
Others, Neuroscience
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CAS Number
299810
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Molecular Formula
C22H30N4O2S
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Molecular Weight
414.56
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SMILES
C(N(C)C1CCCCC1)(=O)C2=CN3C=4C(N=C3S2)=CC=C(CN(CCOC)C)C4
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound