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Molfinity

YM-31636 free base - CAS 159081-22-8

YM-31636 free base - CAS 159081-22-8

MF-0110830-01

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Product Details

  • Bioactivity

    YM-31636 (free base) is an orally active, potent, and selective agonist of the 5-HT3 receptor with a pKi value of 9.67. This compound induces contraction in isolated guinea pig distal colon and provokes tachycardia in isolated guinea pig right atrium, demonstrating a relative intrinsic activity of about 0.23. YM-31636 (free base) holds potential for research in constipation management.

  • Target

    5-HT Receptor

  • Related Pathways

    GPCR/G Protein, Neuroscience

  • CAS Number

    159051

  • Molecular Formula

    C14H11N3S

  • Molecular Weight

    253.32

  • SMILES

    N1=CNC(=C1)CC2=NC=3C=4C=CC=CC4CC3S2

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound