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YM-341619 - CAS 643082-52-4

YM-341619 - CAS 643082-52-4

MF-0036892-01

$1,708.47 USD
$1,228.50 USD $1,708.47 USD
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Product Details

  • Bioactivity

    YM-341619 (AS1617612) is a potent, orally active STAT6 inhibitor (IC50: 0.70 nM) that inhibits IL-4-induced Th2 differentiation in mouse splenic T cells with an IC50 value of 0.28 nM, without affecting Th1 cell differentiation. YM-341619 holds potential for research into allergic diseases, such as allergic asthma.

  • Target

    Others, STAT

  • Related Pathways

    Others, JAK/STAT signaling, Stem Cells

  • CAS Number

    643082-52-4

  • Molecular Formula

    C22H21F3N6O2

  • Molecular Weight

    458.44

  • SMILES

    NC(=O)c1cnc(Nc2ccc(cc2)N2CCOCC2)nc1NCc1c(F)ccc(F)c1F

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound