YM-430 - CAS 153192-22-4

YM-430 is a β1 adrenergic receptor antagonist and a calcium channel antagonist. YM430 could be both an antianginal and antihypertensive agent. YM430 (10 (-8) -10 (-6) M) inhibited 3,4-diaminopyridine-induced rhythmic contractions with an IC50 value of 59.2 nM. In anesthetized rats, YM430 (10-100 mg/kg PO) inhibited arginine vasopressin-induced ST-segment depression with an IC50 value of 36.6 mg/kg PO.

Others, Calcium Channel, Adrenergic Receptor

Others, Metabolism, GPCR/G Protein, Membrane transporter/Ion channel, Neuroscience

153166

C29H35N3O8

553.6

C(OCCCCNC[C@@H](COC1=CC=CC=C1)O)(=O)C=2[C@H](C(C(OC)=O)=C(C)NC2C)C3=CC(N(=O)=O)=CC=C3

-20°C

Ice Packs

Small Compound