YM 511 - CAS 148869-05-0

YM 511 is a highly specific non-steroidal aromatase inhibitor. YM 511 inhibits aromatase activities in microsomes from rat ovary and human placenta competitively (IC50s of 0.4 and 0.12 nM, respectively) . YM 511 slightly inhibits production of other steroid hormones. YM 511 has the potential for suppressing estrogen-dependent action research without affecting serum levels of other steroid hormones.

Aromatase, Cytochromes P450

Endocrinology/Hormones, Metabolism

148869-05-0

>99.99%

C16H12BrN5

354.2

N(CC1=CC=C(Br)C=C1)(C2=CC=C(C#N)C=C2)N3C=NN=C3

-20°C

Ice Packs

Small Compound