YM458 - CAS 2770108-93-3

YM458, a potent dual inhibitor of EZH2 and BRD4, exhibits IC50 values of 490 nM and 34 nM, respectively. This compound effectively hinders cell proliferation and colony formation, while also inducing cell cycle arrest and apoptosis in solid tumor cells, making it a viable candidate for anticancer research [1].

Histone Methyltransferase, Apoptosis, Epigenetic Reader Domain

Chromatin/Epigenetic, Apoptosis

2770012

C53H61ClN8O5S

957.62

-20°C

Ice Packs

Small Compound