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Molfinity

YS-121 - CAS 916482-17-2

YS-121 - CAS 916482-17-2

SKU:MF-0041271-01

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  • Bioactivity

    YS121 is a dual inhibitor of microsomal prostaglandin E2 synthase-1 (mPGES-1; IC50=3.4 μM) and 5-lipoxygenase (5-LOX; IC50=6.5 μM) . YS121 dose-dependently reduces the production of PGE2 with EC50=12 μM in IL-1β-stimulated A549 cells [1].

  • Target

    Others, PGE Synthase, Lipoxygenase

  • Related Pathways

    Metabolism, Immunology/Inflammation, Others

  • CAS Number

    916463

  • Molecular Formula

    C20H26ClN3O2S

  • Molecular Weight

    407.96

  • SMILES

    N(C1=NC(SC(CCCCCC)C(O)=O)=NC(Cl)=C1)C2=C(C)C(C)=CC=C2

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound