YS-67 - CAS 2761327-15-3

YS-67 is an orally available, selective and potent EGFR inhibitor with antitumor activity, inhibits p-EGFR and p-AKT, and inhibits the proliferation of A549, PC-9, and A431 cells.YS-67 blocks cell cycle progression and induces apoptosis in the G0/G1 phase, and can be used in the study of non-small-cell lung cancer.

EGFR, Akt, Apoptosis

JAK/STAT signaling, Angiogenesis, Tyrosine Kinase/Adaptors, Cytoskeletal Signaling, Apoptosis, PI3K/Akt/mTOR signaling

2761327-15-3

0.9888

C32H34N4O3

522.64

N=1C=NC(=C2C=C(OCCCN3CCOCC3)C(OC)=CC12)C=4C=5C=CC=CC5N(C4C=6C=CC=CC6)CC

-20°C

Ice Packs

Small Compound