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YS110 - CAS 1656248-21-3
YS110 - CAS 1656248-21-3
SKU:MF-0100924-01
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Product Details
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Bioactivity
YS110 is a humanized anti-CD26 (DPP4) IgG1 monoclonal antibody. It induces CD26 nuclear translocation via the caveolin pathway and inhibits tumor cell proliferation by delaying the G2/M cell cycle transition. Additionally, YS110 blocks the binding of MERS CoV S1 to CD26, thereby preventing Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infection. This compound is applicable in research on cancer and infections, including malignant mesothelioma and MERS.
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Target
P38 MAPK, Proteasome, ERK
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Related Pathways
Proteases/Proteasome, MAPK, Ubiquitination
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CAS Number
1656248-21-3
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Inhibitory Antibodies