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Molfinity

YUKA1 - CAS 708991-09-7

YUKA1 - CAS 708991-09-7

SKU:MF-0011717-01

Regular price $116.81 USD
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  • Bioactivity

    YUKA1, a cell-permeable KDM5A inhibitor (IC50=2.66 μM) with a weak effect on KDM5C (IC50=7.12 μM) and no effect on other KDM isoforms, was able to increase the level of H3K4me3 in human cells and inhibit the proliferation of cancer cells, and also prevented the emergence of drug-resistant cells.

  • Target

    Histone Demethylase

  • Related Pathways

    Chromatin/Epigenetic

  • CAS Number

    708991-09-7

  • Purity

    0.9985

  • Molecular Formula

    C13H16N4O2S

  • Molecular Weight

    292.36

  • SMILES

    S=C1NN=CN1NCC=2C=CC=C(OC)C2OCC=C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound