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YUM70 - CAS 423145-35-1
YUM70 - CAS 423145-35-1
SKU:MF-0013437-01
Regular price
$40.65 USD
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$40.65 USD
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Product Details
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Bioactivity
YUM70 is a potent and selective inhibitor of glucose-regulated protein 78 (GRP78), with an IC50 of 1.5 μM for inhibiting GRP78 ATPase activity of the full-length protein. It induces endoplasmic reticulum (ER) stress-mediated apoptosis in pancreatic cancer.
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Target
Apoptosis, HSP, GPCR
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Related Pathways
Endocrinology/Hormones, Cytoskeletal Signaling, GPCR/G Protein, Metabolism, Apoptosis
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CAS Number
423109
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Purity
0.9801
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Molecular Formula
C21H19ClN2O4
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Molecular Weight
398.84
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SMILES
CCCC(=O)NC(c1ccc2OCOc2c1)c1cc(Cl)c2cccnc2c1O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound