YY173 - CAS 330550-51-1

YY173 is a dual inhibitor of CDK4 and CDK6, with IC50 values of 7.7 and 88 nM, respectively. It inhibits the proliferation of Jurkat cells with an IC50 of 1.46 μM. Additionally, YY173 can be utilized in the synthesis of PROTAC CDK4/6 degrader 1.

CDK

Cell Cycle/Checkpoint

330550-51-1

C21H25N7O

391.47

O=C1C=NC=2C=NC(=NC2N1C3CCCC3)NC4=CC=C(C=C4)N5CCNCC5

-20°C

Ice Packs

Small Compound