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(Z) -4EGI-1 - CAS 901787-88-0

(Z) -4EGI-1 - CAS 901787-88-0

MF-0011915-01

$121.69 USD
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Product Details

  • Bioactivity

    (Z) -4EGI-1, the Z-isomer of 4EGI-1, serves as an inhibitor of both the eIF4E/eIF4G interaction and translation initiation. It effectively binds to eIF4E, exhibiting an IC50 of 43.5 μM and a Kd value of 8.74 μM. Notably, (Z) -4EGI-1 possesses anticancer activity[1][2].

  • Target

    Others, PERK

  • Related Pathways

    Apoptosis, Others

  • CAS Number

    901787-88-0

  • Molecular Formula

    C18H12Cl2N4O4S

  • Molecular Weight

    451.28

  • SMILES

    N(/N=C(/CC1=C(N(=O)=O)C=CC=C1)\C(O)=O)C2=NC(=CS2)C3=CC(Cl)=C(Cl)C=C3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound