Z-DEVD-R110 - CAS 223538-61-2

Z-DEVD-R110 ((Z-Asp-Glu-Val-Asp) 2 -Rhodamine 110), a rhodamine derivative featuring two four–amino acid (DEVD) peptides attached to the fluorophore [1], serves as a fluorogenic substrate for caspase-3/7. This compound is utilized for detecting apoptosis, leveraging its design to bind and indicate caspase activation.

Others, Apoptosis, Caspase

Proteases/Proteasome, Apoptosis, Others

223538-61-2

C72H78N10O27

1515.44

C([O-])(=O)C1=C(C=2C3=C([O+]=C4C2C=CC(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(OCC5=CC=CC=C5)=O)CC(O)=O)=O)CCC(O)=O)=O)[C@@H](C)C)=O)CC(O)=O)=O)=C4)C=C(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(OCC6=CC=CC=C6)=O)CC(O)=O)=O)CCC(O)=O)=O)C(C)C)=O)CC(O)=O)=O)C=C3)C=CC=C1

-20°C

Ice Packs

Dye-Reagents