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Z-Phe-Ala-diazomethylketone - CAS 71732-53-1
Z-Phe-Ala-diazomethylketone - CAS 71732-53-1
SKU:MF-0157686-01
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Product Details
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Bioactivity
Z-Phe-Ala-diazomethylketone directly binds to Aβ42 monomers and small oligomers, inhibiting Aβ42 dodecamer formation and preventing Aβ42 fibrillogenesis in solution. This compound holds potential for research into neurodegenerative disorders [1].
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Target
Gamma-secretase, Cysteine Protease
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Related Pathways
Neuroscience, Stem Cells, Proteases/Proteasome
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CAS Number
71678
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Molecular Formula
C21H22N4O4
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Molecular Weight
394.42
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SMILES
[C@@H](C(N[C@H](C(C=[N+]=[N-])=O)C)=O)(CC1=CC=CC=C1)NC(OCC2=CC=CC=C2)=O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Peptide