Z-Pro-Pro-aldehyde-dimethyl acetal - CAS 170116-63-9

Z-Pro-Pro-aldehyde-dimethyl acetal is a potent prolyl endopeptidase (PREP) inhibitor, effectively impeding the activity of this cytoplasmic serine endoprotease with an IC50 of 12 nM. Its significance lies in its role in modulating cognitive dysfunction associated with aging and neurodegenerative conditions, such as Alzheimer's disease [1] [2].

Prolyl Endopeptidase (PREP)

Metabolism, Proteases/Proteasome

170044

C20H28N2O5

376.45

C(=O)(N1[C@H](C(OC)OC)CCC1)[C@H]2N(C(OCC3=CC=CC=C3)=O)CCC2

-20°C

Ice Packs

Peptide