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(Z) -Semaxinib - CAS 194413-58-6

(Z) -Semaxinib - CAS 194413-58-6

MF-0014747-01

$33.92 USD
$33.92 USD
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Product Details

  • Bioactivity

    (Z) -Semaxinib (SU5416) is a potent and selective VEGFR (Flk-1/KDR) inhibitor (IC50: 1.23 μM), 20-fold more selective for VEGFR over PDGFRβ, no inhibition for FGFR, InsR, and EGFR. (Z) -Semaxinib is a quinolone derivative with potential antineoplastic activity.

  • Target

    VEGFR, c-Met/HGFR

  • Related Pathways

    Tyrosine Kinase/Adaptors, Angiogenesis

  • CAS Number

    194349

  • Purity

    0.9999

  • Molecular Formula

    C15H14N2O

  • Molecular Weight

    238.28

  • SMILES

    C(=C\1/C=2C(NC1=O)=CC=CC2)\C=3NC(C)=CC3C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound