Z-Val-Val-Nle-diazomethylketone - CAS 155026-49-6

Z-Val-Val-Nle-diazomethylketone is an inhibitor of cathepsin S (CATS) . It significantly suppresses the upregulation of IFNg-induced MHCII molecules, specifically HLA-DR and Ii-p33/35, while increasing the protein level of Ii-p10. This compound can be utilized for research into skin disorders such as psoriasis, atopic dermatitis, and actinic keratosis.

Cysteine Protease, MHC

Immunology/Inflammation, Proteases/Proteasome

155026-49-6

C25H37N5O5

487.59

[C@@H](NC([C@@H](NC([C@@H](NC(OCC1=CC=CC=C1)=O)C(C)C)=O)[C@@H](C)C)=O)(C(C=[N+]=[N-])=O)CCCC

-20°C

Ice Packs

Peptide