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Molfinity

Z1609609733 - CAS 2375374-15-3

Z1609609733 - CAS 2375374-15-3

MF-0118092-01

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Product Details

  • Bioactivity

    Z1609609733 (Compound 18) is a non-covalent inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH) with an IC50 of 1.46 μM. It effectively suppresses serine synthesis, interferes with cancer metabolism, and completely halts cell proliferation.

  • Target

    Dehydrogenase

  • Related Pathways

    Metabolism

  • CAS Number

    2375356

  • Molecular Formula

    C30H27Cl2N3O6

  • Molecular Weight

    596.46

  • SMILES

    O=C(OC(OC(=O)C(C=1C=NC=CC1)C2=CC=C(C=C2)C3(NC(=O)C4=CC=5C(Cl)=C(Cl)C=CC5N4C)COC3)C)C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound