Zamaporvint - CAS 1900754-56-4

Zamaporvint (RXC004) is a selective, orally active and potent inhibitor of the Wnt pathway that acts on the membrane-bound fatty acyltransferase porcupine to block Wnt ligand palmitoylation, secretion, and pathway activation.Zamaporvint has shown anti-tumor and anti-proliferative activity in a wide range of cancer cell lines.

Others, Porcupine, Wnt/beta-catenin, Acyltransferase

Cytoskeletal Signaling, Metabolism, Others, Stem Cells

1900694

0.975

C21H16F3N7O

439.39

O=C(NC1=NC=C(C=C1)C=2N=CC=NC2)CN3C=NC(C=4C=CN=C(C4)C(F)(F)F)=C3C

-20°C

Ice Packs

Small Compound