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Zamicastat - CAS 1080028-80-3

Zamicastat - CAS 1080028-80-3

SKU:MF-0019332-01

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  • Bioactivity

    Zamicastat (BIA 5-1058) is an inhibitor of dopamine β-hydroxylase (DBH) and a concentration-dependent dual inhibitor of P-gp and BCRP, with IC50 values of 73.8 μM and 17.0 μM, respectively.

  • Target

    BCRP, P-gp, Hydroxylase

  • Related Pathways

    Membrane transporter/Ion channel, Neuroscience, Metabolism

  • CAS Number

    1079945

  • Purity

    0.9958

  • Molecular Formula

    C21H21F2N3OS

  • Molecular Weight

    401.47

  • SMILES

    Fc1cc(F)c2OC[C@@H](Cc2c1)n1c(CCNCc2ccccc2)c[nH]c1=S

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound