Zanapezil free base - CAS 142852-50-4

Zanapezil (TAK-147) is a powerful and selective inhibitor of acetylcholine esterase (AChE) . It demonstrates significant and reversible inhibition of AChE activity in rat cerebral cortex homogenates (IC50 = 51.2 nM) . Furthermore, Zanapezil exhibits moderate inhibition of muscarinic M1 and M2 receptor binding with Ki values of 234 and 340 nM, respectively. This compound holds promise for the investigation of the initial stages of Alzheimer's disease (AD) .

Others, Cholinesterase (ChE)

Others, Neuroscience

142798

C25H32N2O

376.544

O=C(CCC1CCN(Cc2ccccc2)CC1)c1ccc2CCCCNc2c1

-20°C

Ice Packs

Small Compound