Zandelisib hydrochloride - CAS 2839515-65-8

Zandelisib (ME-401) hydrochloride is a selective, orally active, non-covalent PI3Kδ inhibitor. It effectively and persistently inhibits AKT phosphorylation and downstream signaling pathways. Zandelisib hydrochloride is utilized in research on malignant tumors such as relapsed/refractory B-cell lymphoma.

PI3K, Akt

PI3K/Akt/mTOR signaling, Cytoskeletal Signaling

2839442

C31H39ClF2N8O

613.14

Cl.FC(F)C1=NC=2C=CC=CC2N1C3=NC(=NC(=N3)N4CCOCC4)NC(C)(C)CC=5C=CC=CC5C6CCN(C)CC6

-20°C

Ice Packs

Small Compound