ZDLD13 - CAS 2762278-95-3

ZDLD13 is a β-carboline that exhibits potent anti-HCT116 activity inclusive of inhibition of invasion and migration, inhibition of colony formation, inducing of apoptosis as well as arresting of G1 phase in cell cycle. ZDLD13 is an orally active and selective inhibitor of CDK4/CycD3 (IC 50 = 0.38 μM) which exhibits significant inhibition of tumor growth in HCT116 tumor xenograft model [1].

Others, Apoptosis, CDK

Apoptosis, Others, Cell Cycle/Checkpoint

2762180

C18H14N4O

302.33

C(NCC1=CC=CC=N1)(=O)C2=C3C(C=4C(N3)=CC=CC4)=CC=N2

-20°C

Ice Packs

Small Compound