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Molfinity

Zelpolib - CAS 701932-26-5

Zelpolib - CAS 701932-26-5

MF-0098354-01

$307.11 USD
$307.11 USD
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Product Details

  • Bioactivity

    Zelpolib is a specific inhibitor of DNA polymerase δ (Pol δ), thereby inhibiting DNA replication and DNA double-strand break homologous recombination repair. It exhibits antiproliferative activity in triple-negative breast cancer cell lines, pancreatic cancer cell lines, and platinum-resistant pancreatic cancer cell lines.

  • Target

    DNA/RNA Synthesis

  • Related Pathways

    DNA Damage/DNA Repair, Cell Cycle/Checkpoint

  • CAS Number

    701901

  • Purity

    0.9879

  • Molecular Formula

    C22H21N3O5S2

  • Molecular Weight

    471.55

  • SMILES

    O=C(OC)C=1C=C(SC1NC(=S)NNC(=O)CCC2=CC=C(O)C(O)=C2)C=3C=CC=CC3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound