Zetomipzomib maleate - CAS 2170983-62-5

Zetomipzomib maleate (KZR-616), a novel immunoproteasome inhibitor, effectively and selectively inhibits the LMP7 subunit (hLMP7/mLMP7 IC50: 39/57 nM) and LMP2 subunit (hLMP7/mLMP7 IC50: 131/179 nM) of the immunoproteasome. This compound shows promising potential for research in various autoimmune diseases.

Others, Proteasome

Others, Proteases/Proteasome, Ubiquitination

2170916

C34H46N4O12

702.758

OC(=O)\C=C/C(O)=O.COc1ccc(cc1)[C@@H](O)[C@H](NC(=O)[C@H](C)NC(=O)CN1CCOCC1)C(=O)N[C@@H](CC1=CCCC1)C(=O)[C@@]1(C)CO1

-20°C

Ice Packs

Small Compound