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ZG-2305 - CAS 2962103-54-2
ZG-2305 - CAS 2962103-54-2
SKU:MF-0110494-01
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Product Details
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Bioactivity
ZG-2305 is a selective, orally active inhibitor of FIH with Ki values of 79.6 nM and 2786 nM for FIH and PHD2, respectively. It increases EGLN3 gene expression, reduces cellular triglyceride levels, and decreases lipid accumulation, making it suitable for obesity and fatty liver disease research.
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Target
HIF
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Related Pathways
Chromatin/Epigenetic, Angiogenesis
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CAS Number
2962047
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Molecular Formula
C17H11Cl2N3O5
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Molecular Weight
408.19
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SMILES
O=C(O)CNC(=O)C=1N=CC(=CC1O)C=2ON=C(C2)C=3C=C(Cl)C=C(Cl)C3
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound