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ZK 216348 - CAS 669073-68-1
ZK 216348 - CAS 669073-68-1
SKU:MF-0034347-01
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Product Details
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Bioactivity
ZK 216348 is a non-steroidal selective glucocorticoid receptor agonist with an IC50 of 20.3 nM. ZK 216348 also binds to progesterone receptors and mineralocorticoid receptors with IC50 values of 20.4 nM and 79.9 nM, respectively, and may be useful for studying inflammatory bowel disease (IBD) .
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Target
Glucocorticoid Receptor, Progesterone Receptor
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Related Pathways
Others, Endocrinology/Hormones
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CAS Number
669004
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Molecular Formula
C24H23F3N2O5
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Molecular Weight
476.45
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SMILES
C(CC(C(NC=1C=C2C(=CC1)C(=O)ON=C2C)=O)(C(F)(F)F)O)(C)(C)C3=C4C(CCO4)=CC=C3
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound