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Molfinity

ZK 756326 - CAS 874911-96-3

ZK 756326 - CAS 874911-96-3

MF-0109566-01

$35.41 USD
$35.41 USD
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Product Details

  • Bioactivity

    ZK 756326 is a selective, non-peptide CCR8 chemokine receptor agonist (IC50: 1.8 μM, in human; 2.6 μM, in mouse) . Displays no activity at CCR4/5 and CXCR3/4 and shows higher 28-fold selectivity over 26 other GPCRs (less selective at α2A and 5-HT receptors) . Induces chemotaxis and inhibits Env-mediated (HIV) cell-cell fusion.

  • Target

    CCR

  • Related Pathways

    GPCR/G Protein, Immunology/Inflammation, Microbiology/Virology

  • CAS Number

    874812

  • Purity

    0.9943

  • Molecular Formula

    C21H28N2O3

  • Molecular Weight

    356.46

  • SMILES

    Cl.Cl.OCCOCCN1CCN(Cc2cccc(Oc3ccccc3)c2)CC1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound